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Home > Anti Cancer > Calitude 50mg - Bicalutamide 50mg




Details for tablet  -  Calitude 50mg - Bicalutamide 50mg



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Product Name
CalitudeTablet  50mg   10 Tablets/Pack (Generic Casodex)

Active Ingredient
Bicalutamide 50mg

Manufacturer
Cipla Pharmaceuticals

Product Type
Treatment of advanced prostate cancer

Calutide Tablets - Product Information
Calutide (Bicalutamide) is used in the treatment of advanced prostate cancer in combination with LHRH analogue therapy. It is available in a blister pack of 10 tablets. Calutide (bicalutamide) Tablets contain 50 mg of bicalutamide which is a non-steroidal androgen receptor inhibitor with no other known endocrine activity.

Name of Drug
Calutide. Sometimes Calutide is also referred to as: Casodex, Cosudex, Kalumid

Active Pharmaceutical Ingredient in Calutide Tablets
The active pharmaceutical ingredient present in Calutide Tablets is Bicalutamide. Each film-coated tablet of Calutide contains 50 mg of Bicalutamide .

Uses of Calutide Tablets
Calutide is used in the treatment of advanced prostate cancer that has spread to other areas of the body. It is prescribed in combination with LHRH analogue therapy. Calutide is used also as monotherapy for early stages of prostate cancer.

Dosage
Take once a day one tablet of Calutide at the same time each day either in the morning or evening. Take it with or without food. Take it regularly to get the most benefit from it.

Drug Class and Mechanism
Calutide is an non-steroidal anti-androgen.
Calutide works by blocking the action of male hormones in the prostate, it slows growth of the tumors.

Missed Dose
Take the dose as soon as you remember. Do not double dose.

Storage Instructions For Calutide Tablets
Store Calutide tablets at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture.

Warnings and Precautions when using Calutide Tablets

Calutide is contraindicated in any patient who has shown a hypersensitivity reaction to Bicalutamide or any of the inactive components. Hypersensitivity reactions including angioneurotic edema and urticaria have been reported. Hepatitis or marked increases in liver enzymes leading to discontinuation of Bicalutamide therapy occurred in approximately 1% of patients in clinical trials. Calutide Tablets should not be taken by women and children.Calutide should not be handled by women who are or may become pregnant, it can cause harm to the fetus.Do not use Calutide together with other medicine which contains terfenadine, astemizole or cisapride.

Before starting to use Calutide tell your doctor, if you have a medical history of liver disease, diabetes, lung/breathing problems.Caution has to be exercised, if Calutide is taken together with  compounds such as cyclosporine, calcium channel blockers and other drugs which may inhibit drug oxidation e.g. cimetidine and ketoconazole. Periodic liver function testing should be considered due to the possibility of hepatic changes.

Side Effects of Calutide Tablets
Listed below are the possible side effects of Calutide tablets:

  • Flushing and sweating (hot flashes)
  • Body aches and pains
  • Breast swelling/tenderness/pain
  • Headache
  • dizziness, drowsiness
  • Insomnia
  • Weight changes
  • Hair loss
  • Constipation or diarrhea,
  • Stomach upset, gas
  • Nausea, vomiting

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